(Fig 5-C.04) Delamination and Graft Failure of hUCB-MSCs Implantation

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📌 Delamination

 

• Delamination can be identified by displacement of all or a portion of the graft from the repair site or linear high signal intensity between the repair tissue and underlying bone. 
• Subjacent edemalike marrow signal intensity is usually present when delamination has occurred.

 

✅ Indicators of Poor Integration

• A linear high signal intensity between the repair tissue and underlying bone, representing delamination, may indicate a poor integration of the repair tissue and potential treatment failure.

• In delamination of surgically repaired cartilage, there is failure of the repair tissue to integrate with the subchondral bone, resulting in separation of the repaired cartilage from the underlying subchondral bone.

 

References

1. Radiology 2015; 277:23–43
2. Semin Musculoskelet Radiol 2022;26:216–229
3. MRI Web Clinic – June 2021 Tissue Delamination

 

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#Delamination, #Radiology, #MRI, #CartilageRepair, #SubchondralBone, #MedicalImaging, #TissueIntegration, #SurgicalRepair, #BoneMarrowEdema, #MusculoskeletalRadiology