(Fig 5-E.10) Localized-type Tenosynovial Giant Cell Tumor

https://youtu.be/Q-p4GdqQT1g

 

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Visualizing MSK Radiology: A Practical Guide to Radiology Mastery

 

MSK MRI Jee Eun Lee

 

 

📌 Tenosynovial Giant Cell Tumor

 

• Tenosynovial giant cell tumor (TGCT) is a benign synovial proliferative disorder characterized by villous and nodular projections. 
• The disease may present as either localized or diffuse and is usually monoarticular, meaning it typically affects only one joint.

 

✅ Two types of TGCT

• Localized TGCT: Also known as focal form, formerly referred to as focal nodular synovitis.
  This form is usually small, ovoid, and exhibits intermediate or low signal intensity on MRI sequences.
  
  
• Diffuse TGCT: Formerly known as pigmented villonodular synovitis,
  this form shows similar histological features as the localized form but involves a more extensive area of the synovium.

 

✅ MRI Characteristics

• Signal Intensity: TGCT is characterized by recurrent bleeding, which leads to hemosiderin deposition.
  This causes a characteristic low signal intensity in all MRI sequences and magnetic susceptibility.
  
  
• Localized TGCT: Most commonly appears as a small (2-3 cm) ovoid mass with intermediate or low signal intensity.
  Larger polylobulated lesions are not uncommon.
  In the knee, the infrapatellar fat pad is affected in two-thirds of cases, with the remainder located at the suprapatellar pouch or intercondylar notch.

 

References

• Radiographics. 2023 May;43(5)
  .
• RadioGraphics 2018; 38:2069–2101.

 

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