(Fig 5-A.05) T2 Mapping Techniques

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https://youtu.be/YyQWPfrVkxI

 

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📌 T2 Mapping Techniques

 

✅ Clinical Significance

• T2 mapping measures the spatial distribution of T2 to identify areas of increased and decreased water content. 
• This allows for the quantification of cartilage degeneration before morphological changes are visible.

 

✅ Age-Related Changes and Damage Detection

• With aging, articular cartilage shows a diffuse increase in T2 relaxation values, while damaged cartilage shows focally increased T2 values.

 

✅  Case Study: Cartilage Repair

• In cartilage repair patients, lower T2 values are observed in the repair area compared to normal cartilage. 
• Higher T2 values are visible in native cartilage at locations where the radial zone is positioned at 55° to the main magnetic field, due to the magic angle effect.

 

✅ Characterizing Cartilage Composition

• T2 mapping is a valuable tool for diagnosing and monitoring cartilage health and repair. 
• It characterizes the biochemical composition of cartilage at both native and repair sites within the knee. 
• This technique is particularly useful for evaluating cartilage repair tissue after procedures such as microfracture, osteochondral grafting, and matrix-assisted autologous transplantation. 
• Additionally, it helps assess graft maturation following autologous chondrocyte implantation.

• T2 mapping is a sensitive biomarker for evaluating early chondral degeneration. 
• It can be easily implemented on clinical routine MR scanners.

References

J Clin Orthop Trauma. 2021 Sep 25;22:101610

 

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#T2Mapping, #CartilageHealth, #ChondralDegeneration, #MRIScanners, #CartilageRepair, #MagicAngleEffect, #Biomarkers, #Orthopedics, #MedicalImaging, #KneeSurgery