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📌 T2 Mapping Techniques
✅ Clinical Significance
- T2 mapping measures the spatial distribution of T2 to identify areas of increased and decreased water content.
- This allows for the quantification of cartilage degeneration before morphological changes are visible.
✅ Age-Related Changes and Damage Detection
- With aging, articular cartilage shows a diffuse increase in T2 relaxation values, while damaged cartilage shows focally increased T2 values.
✅ Case Study: Cartilage Repair
- In cartilage repair patients, lower T2 values are observed in the repair area compared to normal cartilage.
- Higher T2 values are visible in native cartilage at locations where the radial zone is positioned at 55° to the main magnetic field, due to the magic angle effect.
✅ Characterizing Cartilage Composition
- T2 mapping is a valuable tool for diagnosing and monitoring cartilage health and repair.
- It characterizes the biochemical composition of cartilage at both native and repair sites within the knee.
- This technique is particularly useful for evaluating cartilage repair tissue after procedures such as microfracture, osteochondral grafting, and matrix-assisted autologous transplantation.
- Additionally, it helps assess graft maturation following autologous chondrocyte implantation.
- T2 mapping is a sensitive biomarker for evaluating early chondral degeneration.
- It can be easily implemented on clinical routine MR scanners.
References
J Clin Orthop Trauma. 2021 Sep 25;22:101610
"Visualizing MSK Radiology: A Practical Guide to Radiology Mastery"
© 2022 MSK MRI Jee Eun Lee All Rights Reserved.
No unauthorized reproduction, redistribution, or use for AI training.
#T2Mapping, #CartilageHealth, #ChondralDegeneration, #MRIScanners, #CartilageRepair, #MagicAngleEffect, #Biomarkers, #Orthopedics, #MedicalImaging, #KneeSurgery
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